Why Most Published Research Findings Are False

Creators

• John P. A. Ioannidis, author

Canon Rationale

A central reproducibility and meta-research paper, included for research validity, bias, power, false positives, and the modern open-science/reproducibility debate.

Evidence

• citation context: John P. A. Ioannidis, 'Why Most Published Research Findings Are False,' PLOS Medicine 2(8): e124, 2005.
• field survey: Nature Genetics, 'Researching the researchers'.

Audit Flags

epistemic status required