DNA Sequencing with Chain-Terminating Inhibitors

Creators

• Frederick Sanger, author
• Steven Nicklen, author
• Alan R. Coulson, author

Canon Rationale

A major genomics methods paper, included for chain-termination sequencing and the technical route that made modern DNA sequencing practical.

Evidence

• citation context: Sanger et al., 'DNA sequencing with chain-terminating inhibitors,' PNAS, 1977.
• field survey: The Nobel Prize, Frederick Sanger chemistry prize materials.

Audit Flags

version dependency, epistemic status required